What the FDA labels say about taking them together
Cholic acid and colestipol
Cholic acid's FDA label of January 26, 2026 names colestipol in its drug interactions section; the colestipol labels PlainMeds reads (3) do not name cholic acid. The cholic acid label: “Bile Acid Binding Resins Bile acid binding resins such as cholestyramine, colestipol, or colesevelam adsorb and reduce bile acid absorption and may reduce the efficacy of CHOLBAM.”
Check it at the source: the cholic acid FDA label on DailyMed (effective January 26, 2026, Mirum Pharmaceuticals Inc.); the colestipol FDA label on DailyMed (effective February 19, 2024, Zydus Pharmaceuticals USA Inc.).
What does the cholic acid label say about colestipol?
Cholic acid label, drug interactionsBile Acid Binding Resins Bile acid binding resins such as cholestyramine, colestipol, or colesevelam adsorb and reduce bile acid absorption and may reduce the efficacy of CHOLBAM.
Source: FDA drug label (CHOLBAM), Mirum Pharmaceuticals Inc., effective January 26, 2026 (SPL set 5c6e4c9d-b85e-493f-9420-ab2fd0ff3723), via openFDA; the full label on DailyMed
What does the colestipol label say about cholic acid?
Colestipol's label (effective February 19, 2024) and its 2 other brand-application labels do not name cholic acid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Colestipol hydrochloride), Zydus Pharmaceuticals USA Inc., effective February 19, 2024 (SPL set 71f12e0d-373a-4867-b37c-f24d99c5ce95), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cholic acid | Colestipol | |
|---|---|---|
| Labeled for | n/a | High cholesterol |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.658 per tablet 1 g tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once