What the FDA labels say about taking them together
Cholestyramine and ursodiol
Ursodiol's FDA label of July 31, 2023 names cholestyramine in its drug interactions section; the cholestyramine label PlainMeds reads does not name ursodiol.
Check it at the source: the cholestyramine FDA label on DailyMed (effective August 20, 2026, AiPing Pharmaceutical, Inc.); the ursodiol FDA label on DailyMed (effective July 31, 2023, Actavis Pharma, Inc.).
What does the cholestyramine label say about ursodiol?
Cholestyramine's label (effective August 20, 2026) does not name ursodiol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cholestyramine), AiPing Pharmaceutical, Inc., effective August 20, 2026 (SPL set 214ea05f-de81-4026-9df9-4ce3820668ee), via openFDA; the full label on DailyMed
What does the ursodiol label say about cholestyramine?
Ursodiol label, drug interactionsDrug Interactions Bile acid sequestering agents such as cholestyramine and colestipol may interfere with the action of ursodiol by reducing its absorption.
Source: FDA drug label (Urso 250, NDA020675), Allergan, Inc., effective January 12, 2023 (SPL set e8fc4fc2-fe5c-4cba-b6e0-5ceaf2157a61), via openFDA
Source: FDA drug label (Ursodiol), Actavis Pharma, Inc., effective July 31, 2023 (SPL set a061bb07-a85d-4b08-877f-ce02156f0de7), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cholestyramine | Ursodiol | |
|---|---|---|
| Labeled for | High cholesterol | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.834 per packet Cholestyramine packet | $0.429 per capsule 300 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once