Skip to main content

What the FDA labels say about taking them together

Cholestyramine and tinidazole

Tinidazole's FDA label of December 27, 2021 names cholestyramine in its drug interactions section; the cholestyramine label PlainMeds reads does not name tinidazole. The tinidazole label: “Cholestyramine: Cholestyramine was shown to decrease the oral bioavailability of metronidazole by 21%.”

Check it at the source: the cholestyramine FDA label on DailyMed (effective August 20, 2026, AiPing Pharmaceutical, Inc.); the tinidazole FDA label on DailyMed (effective December 27, 2021, Mission Pharmacal Company).

What does the cholestyramine label say about tinidazole?

Cholestyramine's label (effective August 20, 2026) does not name tinidazole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Cholestyramine), AiPing Pharmaceutical, Inc., effective August 20, 2026 (SPL set 214ea05f-de81-4026-9df9-4ce3820668ee), via openFDA; the full label on DailyMed

What does the tinidazole label say about cholestyramine?

Tinidazole label, drug interactions

Cholestyramine: Cholestyramine was shown to decrease the oral bioavailability of metronidazole by 21%.

Source: FDA drug label (Tindamax), Mission Pharmacal Company, effective December 27, 2021 (SPL set a0d01539-8413-4703-94cc-d221918630a1), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

15Cholestyramine generic labelers
5Tinidazole generic labelers
CholestyramineTinidazole
Labeled forHigh cholesteroln/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.834 per packet Cholestyramine packet$2.35 per tablet 500 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?