What the FDA labels say about taking them together
Cholestyramine and teriflunomide
Teriflunomide's FDA label of February 20, 2026 names cholestyramine in its boxed warning section; the cholestyramine label PlainMeds reads does not name teriflunomide. The teriflunomide label: “WARNINGS AND PRECAUTIONS Elimination of AUBAGIO can be accelerated by administration of cholestyramine or activated charcoal for 11 days. AUBAGIO may decrease WBC.”
Check it at the source: the cholestyramine FDA label on DailyMed (effective August 20, 2026, AiPing Pharmaceutical, Inc.); the teriflunomide FDA label on DailyMed (effective February 20, 2026, Genzyme Corporation).
What does the cholestyramine label say about teriflunomide?
Cholestyramine's label (effective August 20, 2026) does not name teriflunomide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cholestyramine), AiPing Pharmaceutical, Inc., effective August 20, 2026 (SPL set 214ea05f-de81-4026-9df9-4ce3820668ee), via openFDA; the full label on DailyMed
What does the teriflunomide label say about cholestyramine?
Teriflunomide label, boxed warningIf drug induced liver injury is suspected, discontinue AUBAGIO and start an accelerated elimination procedure with cholestyramine or charcoal [see Warnings and Precautions (5.3) ].
Teriflunomide label, warnings and precautionsWARNINGS AND PRECAUTIONS Elimination of AUBAGIO can be accelerated by administration of cholestyramine or activated charcoal for 11 days. ( 5.3 ) AUBAGIO may decrease WBC.
Source: FDA drug label (Aubagio), NDA202992 (Sanofi Aventis Us), as published by Genzyme Corporation, effective February 20, 2026 (SPL set 4650d12c-b9c8-4525-b07f-a2d773eca155), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cholestyramine | Teriflunomide | |
|---|---|---|
| Labeled for | High cholesterol | Multiple sclerosis |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.834 per packet Cholestyramine packet | $0.233 per tablet 14 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once