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What the FDA labels say about taking them together

Cholestyramine and maralixibat

Maralixibat's FDA label of April 10, 2025 names cholestyramine in its drug interactions section; the cholestyramine label PlainMeds reads does not name maralixibat.

Check it at the source: the cholestyramine FDA label on DailyMed (effective August 20, 2026, AiPing Pharmaceutical, Inc.); the maralixibat FDA label on DailyMed (effective April 10, 2025, Mirum Pharmaceuticals Inc.).

What does the cholestyramine label say about maralixibat?

Cholestyramine's label (effective August 20, 2026) does not name maralixibat in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Cholestyramine), AiPing Pharmaceutical, Inc., effective August 20, 2026 (SPL set 214ea05f-de81-4026-9df9-4ce3820668ee), via openFDA; the full label on DailyMed

What does the maralixibat label say about cholestyramine?

Maralixibat label, drug interactions

Administer LIVMARLI at least 4 hours before or 4 hours after administration of bile acid binding resins (e.g., cholestyramine, colesevelam, or colestipol).

Source: FDA drug label (Livmarli), Mirum Pharmaceuticals Inc., effective April 10, 2025 (SPL set 64000394-1ef6-4e76-8ba8-11f25ba1b167), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

15Cholestyramine generic labelers
0Maralixibat generic labelers
CholestyramineMaralixibat
Labeled forHigh cholesteroln/a
Boxed warningNoNo
Pharmacy cost (NADAC)$0.834 per packet Cholestyramine packetn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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