What the FDA labels say about taking them together
Cholestyramine and folic acid
Folic acid's FDA label (Folic Acid) of February 11, 2026 names cholestyramine in its drug interactions section; the cholestyramine label PlainMeds reads does not name folic acid.
Check it at the source: the cholestyramine FDA label on DailyMed (effective August 20, 2026, AiPing Pharmaceutical, Inc.); the folic acid FDA label on DailyMed (effective July 24, 2026, Rising Pharma Holdings, Inc.).
What does the cholestyramine label say about folic acid?
Cholestyramine's label (effective August 20, 2026) does not name folic acid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cholestyramine), AiPing Pharmaceutical, Inc., effective August 20, 2026 (SPL set 214ea05f-de81-4026-9df9-4ce3820668ee), via openFDA; the full label on DailyMed
What does the folic acid label say about cholestyramine?
Folic Acid label (Ayurax, LLC, February 11, 2026), drug interactionsAdditional agents such as pentamidine, antacids, cholestyramine, colestipol, and H 2 blockers impair gastrointestinal folate uptake through pH elevation, transporter inhibition, or binding of dietary folate.
Source: FDA drug label (Folic Acid, NDA216395), Ayurax, LLC, effective February 11, 2026 (SPL set 96618bf8-6c03-4df3-9896-b7ef27ca392a), via openFDA
Source: FDA drug label (Folic Acid), Rising Pharma Holdings, Inc., effective July 24, 2026 (SPL set 0baa10dd-6d1d-4946-8236-566451132da3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cholestyramine | Folic acid | |
|---|---|---|
| Labeled for | High cholesterol | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.834 per packet Cholestyramine packet | $0.0201 per tablet 1 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once