What the FDA labels say about taking them together
Cholestyramine and cholic acid
Cholic acid's FDA label of January 26, 2026 names cholestyramine in its drug interactions section; the cholestyramine label PlainMeds reads does not name cholic acid. The cholic acid label: “Bile Acid Binding Resins Bile acid binding resins such as cholestyramine, colestipol, or colesevelam adsorb and reduce bile acid absorption and may reduce the efficacy of CHOLBAM.”
Check it at the source: the cholestyramine FDA label on DailyMed (effective August 20, 2026, AiPing Pharmaceutical, Inc.); the cholic acid FDA label on DailyMed (effective January 26, 2026, Mirum Pharmaceuticals Inc.).
What does the cholestyramine label say about cholic acid?
Cholestyramine's label (effective August 20, 2026) does not name cholic acid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cholestyramine), AiPing Pharmaceutical, Inc., effective August 20, 2026 (SPL set 214ea05f-de81-4026-9df9-4ce3820668ee), via openFDA; the full label on DailyMed
What does the cholic acid label say about cholestyramine?
Cholic acid label, drug interactionsBile Acid Binding Resins Bile acid binding resins such as cholestyramine, colestipol, or colesevelam adsorb and reduce bile acid absorption and may reduce the efficacy of CHOLBAM.
Source: FDA drug label (CHOLBAM), Mirum Pharmaceuticals Inc., effective January 26, 2026 (SPL set 5c6e4c9d-b85e-493f-9420-ab2fd0ff3723), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cholestyramine | Cholic acid | |
|---|---|---|
| Labeled for | High cholesterol | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.834 per packet Cholestyramine packet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once