What the FDA labels say about taking them together
Chloroquine and tafenoquine
Tafenoquine's FDA label (Krintafel) of August 2, 2023 names chloroquine in its warnings and precautions section; the chloroquine label PlainMeds reads does not name tafenoquine. The tafenoquine label: “Use with antimalarials other than chloroquine is not recommended.”
Check it at the source: the chloroquine FDA label on DailyMed (effective July 2, 2026, Rising Pharma Holdings, Inc.); the tafenoquine FDA label on DailyMed (effective January 10, 2025, 60 Degrees Pharmaceuticals, INC.).
What does the chloroquine label say about tafenoquine?
Chloroquine's label (effective July 2, 2026) does not name tafenoquine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Chloroquine Phosphate), Rising Pharma Holdings, Inc., effective July 2, 2026 (SPL set 06c69e2b-211b-4746-9f3a-f86d36520570), via openFDA; the full label on DailyMed
What does the tafenoquine label say about chloroquine?
Krintafel label (GlaxoSmithKline LLC, August 2, 2023), warnings and precautionsUse with antimalarials other than chloroquine is not recommended.
Source: FDA drug label (Krintafel, NDA210795), GlaxoSmithKline LLC, effective August 2, 2023 (SPL set 5cf989d5-36f5-4561-a30b-9fcb9deb6b6a), via openFDA
Source: FDA drug label (Arakoda), 60 Degrees Pharmaceuticals, INC., effective January 10, 2025 (SPL set 299e49d8-470f-4779-a010-4a1ee0e0c6cd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Chloroquine | Tafenoquine | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $6.65 per tablet 500 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once