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What the FDA labels say about taking them together

Chloroquine and succinylcholine

Succinylcholine's FDA label of August 18, 2026 names chloroquine in its drug interactions section; the chloroquine label PlainMeds reads does not name succinylcholine. The succinylcholine label: “… procainamide, lidocaine, trimethaphan, lithium carbonate, magnesium salts, quinine, chloroquine, isoflurane, desflurane, metoclopramide, terbutaline, and drugs that reduce plasma cholinesterase activity.”

Check it at the source: the chloroquine FDA label on DailyMed (effective July 2, 2026, Rising Pharma Holdings, Inc.); the succinylcholine FDA label on DailyMed (effective August 18, 2026, Hospira, Inc.).

What does the chloroquine label say about succinylcholine?

Chloroquine's label (effective July 2, 2026) does not name succinylcholine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Chloroquine Phosphate), Rising Pharma Holdings, Inc., effective July 2, 2026 (SPL set 06c69e2b-211b-4746-9f3a-f86d36520570), via openFDA; the full label on DailyMed

What does the succinylcholine label say about chloroquine?

Succinylcholine label, drug interactions

DRUG INTERACTIONS Drugs that May Enhance the Neuromuscular Blocking Action of Succinylcholine: promazine, oxytocin, aprotinin, certain non-penicillin antibiotics, quinidine, β-adrenergic blockers, procainamide, lidocaine, trimethaphan, lithium carbonate, magnesium salts, quinine, chloroquine, isoflurane, desflurane, metoclopramide, terbutaline, and drugs that reduce plasma cholinesterase activity.

Source: FDA drug label (QUELICIN), Hospira, Inc., effective August 18, 2026 (SPL set fb08161e-7711-406d-e7b3-ea4515c07983), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Chloroquine generic labelers
26Succinylcholine generic labelers
ChloroquineSuccinylcholine
Labeled forn/an/a
Boxed warningNoYes
Pharmacy cost (NADAC)$6.65 per tablet 500 mg tabletn/a
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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