Skip to main content

What the FDA labels say about taking them together

Chloramphenicol and glyburide

Glyburide's FDA label of July 1, 2021 names chloramphenicol in its drug interactions section; the chloramphenicol label PlainMeds reads does not name glyburide.

Check it at the source: the chloramphenicol FDA label on DailyMed (effective October 10, 2024, Fresenius Kabi USA, LLC); the glyburide FDA label on DailyMed (effective July 1, 2021, TEVA Pharmaceuticals USA Inc).

What does the chloramphenicol label say about glyburide?

Chloramphenicol's label (effective October 10, 2024) does not name glyburide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Chloramphenicol Sodium Succinate), Fresenius Kabi USA, LLC, effective October 10, 2024 (SPL set aed29594-211d-49ef-813f-131975a8d0e3), via openFDA; the full label on DailyMed

What does the glyburide label say about chloramphenicol?

Glyburide label, drug interactions

Drug Interactions The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents, ACE inhibitors, disopyramide, fluoxetine, clarithromycin, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, monoamine oxidase inhibitors, and beta adrenergic blocking agents.

Source: FDA drug label (Glyburide), NDA017532 (Sanofi Aventis Us), as published by TEVA Pharmaceuticals USA Inc, effective July 1, 2021 (SPL set 50d16f1d-c814-4411-8749-62561321ecce), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Chloramphenicol generic labelers
16Glyburide generic labelers
ChloramphenicolGlyburide
Labeled forn/aType 2 diabetes
Boxed warningYesNo
Pharmacy cost (NADAC)n/a$0.0643 per tablet 5 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?