What the FDA labels say about taking them together
Cetuximab and cisplatin
Cetuximab's FDA label of April 16, 2026 names cisplatin in its warnings and precautions section; the cisplatin label PlainMeds reads does not name cetuximab. The cetuximab label: “… rash, cardiac events, and electrolyte disturbances compared to radiation and cisplatin alone.”
Check it at the source: the cetuximab FDA label on DailyMed (effective April 16, 2026, ImClone LLC); the cisplatin FDA label on DailyMed (effective September 16, 2021, WG Critical Care, LLC).
What does the cetuximab label say about cisplatin?
Cetuximab label, warnings and precautionsThe addition of ERBITUX resulted in an increase in the incidence of Grade 3 and 4 mucositis, radiation recall syndrome, acneiform rash, cardiac events, and electrolyte disturbances compared to radiation and cisplatin alone.
Source: FDA drug label (ERBITUX), ImClone LLC, effective April 16, 2026 (SPL set 8bc6397e-4bd8-4d37-a007-a327e4da34d9), via openFDA; the full label on DailyMed
What does the cisplatin label say about cetuximab?
Cisplatin's label (effective September 16, 2021) does not name cetuximab in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (CISplatin), NDA018057 (Hq Spclt Pharma), as published by WG Critical Care, LLC, effective September 16, 2021 (SPL set 2bf8d2fb-80c8-401d-8e9b-d58463f5e954), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cetuximab | Cisplatin | |
|---|---|---|
| Labeled for | Colorectal cancer | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once