What the FDA labels say about taking them together
Ceritinib and clonidine
Ceritinib's FDA label of December 15, 2025 names clonidine in its warnings and precautions section; the clonidine labels PlainMeds reads (4) do not name ceritinib. The ceritinib label: “Avoid using ZYKADIA in combination with other products known to cause bradycardia to the extent possible. Monitor heart rate and blood pressure regularly.”
Check it at the source: the ceritinib FDA label on DailyMed (effective December 15, 2025, Novartis Pharmaceuticals Corporation); the clonidine FDA label on DailyMed (effective March 30, 2026, Unichem Pharmaceuticals (USA), Inc.).
What does the ceritinib label say about clonidine?
Ceritinib label, warnings and precautionsAvoid using ZYKADIA in combination with other products known to cause bradycardia (e.g., beta-blockers, non-dihydropyridine calcium channel blockers, clonidine, and digoxin) to the extent possible. Monitor heart rate and blood pressure regularly.
Source: FDA drug label (ZYKADIA), Novartis Pharmaceuticals Corporation, effective December 15, 2025 (SPL set fff5d805-4ffd-4e8e-8e63-6f129697563e), via openFDA; the full label on DailyMed
What does the clonidine label say about ceritinib?
Clonidine's label (effective March 30, 2026) and its 3 other brand-application labels do not name ceritinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (clonidine hydrochloride), Unichem Pharmaceuticals (USA), Inc., effective March 30, 2026 (SPL set 21bfa28f-20df-43fd-bb80-b720d3b40696), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ceritinib | Clonidine | |
|---|---|---|
| Labeled for | Lung cancer | High blood pressure, ADHD, Pain |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.0241 per tablet 0.1 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once