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What the FDA labels say about taking them together

Castor oil and valrubicin

Valrubicin's FDA label of October 31, 2024 names castor oil in its contraindications section; the castor oil label PlainMeds reads does not name valrubicin. The valrubicin label: “CONTRAINDICATIONS VALSTAR is contraindicated in patients with: Perforated bladder [ see Warnings and Precautions] Known hypersensitivity to anthracyclines or polyoxyl castor oil Active urinary tract infection Small …”

Check it at the source: the castor oil FDA label on DailyMed (effective June 15, 2026); the valrubicin FDA label on DailyMed (effective October 31, 2024, Endo USA, Inc.).

What does the castor oil label say about valrubicin?

Castor oil's label (effective June 15, 2026) does not name valrubicin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Signature Care), Better Living Brands, LLC, effective June 15, 2026 (SPL set 4947cf4d-3ebd-4b66-9582-f141407aa300), via openFDA; the full label on DailyMed

What does the valrubicin label say about castor oil?

Valrubicin label, contraindications

CONTRAINDICATIONS VALSTAR is contraindicated in patients with: Perforated bladder [ see Warnings and Precautions ( 5.2 )] Known hypersensitivity to anthracyclines or polyoxyl castor oil Active urinary tract infection Small bladder capacity and unable to tolerate a 75 mL instillation Perforated bladder or compromised bladder mucosa ( 4 , 5.2 ) Hypersensitivity to anthracyclines or polyoxyl castor oil. ( 4 ) Concurrent urinary tract infections. ( 4 ) Patients with a small bladder capacity unable to tolerate a 75 mL instillation.

Source: FDA drug label (Valstar), Endo USA, Inc., effective October 31, 2024 (SPL set e96f30a0-6662-11de-8f80-0002a5d5c51b), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Castor oil generic labelers
1Valrubicin generic labelers
Castor oilValrubicin
Labeled forConstipationn/a
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0193 per mL Castor oiln/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?