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What the FDA labels say about taking them together

Castor oil and paclitaxel

Paclitaxel's FDA label of January 21, 2026 names castor oil in its contraindications section; the castor oil label PlainMeds reads does not name paclitaxel. The paclitaxel label: “CONTRAINDICATIONS Paclitaxel Injection, USP is contraindicated in patients who have a history of hypersensitivity reactions to paclitaxel or other drugs formulated in Polyoxyl 35 Castor Oil, NF.”

Check it at the source: the castor oil FDA label on DailyMed (effective June 15, 2026); the paclitaxel FDA label on DailyMed (effective January 21, 2026, Natco Pharma USA LLC).

What does the castor oil label say about paclitaxel?

Castor oil's label (effective June 15, 2026) does not name paclitaxel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Signature Care), Better Living Brands, LLC, effective June 15, 2026 (SPL set 4947cf4d-3ebd-4b66-9582-f141407aa300), via openFDA; the full label on DailyMed

What does the paclitaxel label say about castor oil?

Paclitaxel label, contraindications

CONTRAINDICATIONS Paclitaxel Injection, USP is contraindicated in patients who have a history of hypersensitivity reactions to paclitaxel or other drugs formulated in Polyoxyl 35 Castor Oil, NF.

Source: FDA drug label (Paclitaxel), Natco Pharma USA LLC, effective January 21, 2026 (SPL set a1eb16b4-285b-4e81-9c4e-1244d4a52af8), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Castor oil generic labelers
19Paclitaxel generic labelers
Castor oilPaclitaxel
Labeled forConstipationBreast cancer, Lung cancer
Boxed warningNoYes
Pharmacy cost (NADAC)$0.0193 per mL Castor oiln/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?