What the FDA labels say about taking them together
Castor oil and cyclosporine
Cyclosporine's FDA label (Sandimmune) of July 10, 2026 names castor oil in its contraindications section; the castor oil label PlainMeds reads does not name cyclosporine. The cyclosporine label: “Sandimmune injection is also contraindicated in patients with a history of a hypersensitivity reaction to Cremophor ® EL.”
Check it at the source: the castor oil FDA label on DailyMed (effective June 15, 2026); the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation).
What does the castor oil label say about cyclosporine?
Castor oil's label (effective June 15, 2026) does not name cyclosporine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Signature Care), Better Living Brands, LLC, effective June 15, 2026 (SPL set 4947cf4d-3ebd-4b66-9582-f141407aa300), via openFDA; the full label on DailyMed
What does the cyclosporine label say about castor oil?
Sandimmune label (Novartis Pharmaceuticals Corporation, July 10, 2026), contraindicationsSandimmune injection is also contraindicated in patients with a history of a hypersensitivity reaction to Cremophor ® EL (polyoxyethylated castor oil).
Source: FDA drug label (Sandimmune, NDA050573), Novartis Pharmaceuticals Corporation, effective July 10, 2026 (SPL set 5e5926a7-1de0-4b54-a5c0-286b6200ff82), via openFDA
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Castor oil | Cyclosporine | |
|---|---|---|
| Labeled for | Constipation | Organ transplant rejection, Rheumatoid arthritis |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.0193 per mL Castor oil | $1.04 per unit 0.05% eye emulsion |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once