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What the FDA labels say about taking them together

Carvedilol and ubrogepant

Ubrogepant's FDA label of June 5, 2025 names carvedilol in its drug interactions section; the carvedilol labels PlainMeds reads (2) do not name ubrogepant. The ubrogepant label: “Use of BCRP and/or P-gp only inhibitors may increase the exposure of ubrogepant [ s ee Clinical Pharmacology ].”

Check it at the source: the carvedilol FDA label on DailyMed (effective July 31, 2026, Waylis Therapeutics LLC); the ubrogepant FDA label on DailyMed (effective June 5, 2025, Allergan, Inc.).

What does the carvedilol label say about ubrogepant?

Carvedilol's label (effective July 31, 2026) and its 1 other brand-application label do not name ubrogepant in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Coreg), Waylis Therapeutics LLC, effective July 31, 2026 (SPL set 07c619c6-4a0c-445e-94fa-664a54f68a39), via openFDA; the full label on DailyMed

What does the ubrogepant label say about carvedilol?

Ubrogepant label, drug interactions

Use of BCRP and/or P-gp only inhibitors (e.g., quinidine, carvedilol, eltrombopag, curcumin) may increase the exposure of ubrogepant [ s ee Clinical Pharmacology ( 12.3 ) ].

Source: FDA drug label (UBRELVY), NDA211765 (Abbvie), as published by Allergan, Inc., effective June 5, 2025 (SPL set fd9f9458-fd96-4688-be3f-f77b3d1af6ab), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

41Carvedilol generic labelers
0Ubrogepant generic labelers
CarvedilolUbrogepant
Labeled forHeart failure, High blood pressureMigraine
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0179 per tablet 6.25 mg tablet$109.11 per tablet 100 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?