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What the FDA labels say about taking them together

Carvedilol and talazoparib

Talazoparib's FDA label of April 10, 2026 names carvedilol in its drug interactions section; the carvedilol labels PlainMeds reads (2) do not name talazoparib. The talazoparib label: “Drugs on TALZENNA Effect of P-gp Inhibitors Breast Cancer Avoid coadministration of TALZENNA with the following P-gp inhibitors: itraconazole, amiodarone, carvedilol, clarithromycin, itraconazole, and verapamil.”

Check it at the source: the carvedilol FDA label on DailyMed (effective July 31, 2026, Waylis Therapeutics LLC); the talazoparib FDA label on DailyMed (effective April 10, 2026, Pfizer Laboratories Div Pfizer Inc).

What does the carvedilol label say about talazoparib?

Carvedilol's label (effective July 31, 2026) and its 1 other brand-application label do not name talazoparib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Coreg), Waylis Therapeutics LLC, effective July 31, 2026 (SPL set 07c619c6-4a0c-445e-94fa-664a54f68a39), via openFDA; the full label on DailyMed

What does the talazoparib label say about carvedilol?

Talazoparib label, drug interactions

Drugs on TALZENNA Effect of P-gp Inhibitors Breast Cancer Avoid coadministration of TALZENNA with the following P-gp inhibitors: itraconazole, amiodarone, carvedilol, clarithromycin, itraconazole, and verapamil.

Source: FDA drug label (Talzenna), Pfizer Laboratories Div Pfizer Inc, effective April 10, 2026 (SPL set c6fd147f-a77e-4a0b-9280-e82ecc41b4be), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

41Carvedilol generic labelers
0Talazoparib generic labelers
CarvedilolTalazoparib
Labeled forHeart failure, High blood pressureBreast cancer, Prostate cancer
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0179 per tablet 6.25 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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