What the FDA labels say about taking them together
Carvedilol and cinacalcet
Cinacalcet's FDA label of April 2, 2026 names carvedilol in its drug interactions section; the carvedilol labels PlainMeds reads (2) do not name cinacalcet. The cinacalcet label: “Dose adjustments may be required for concomitant medications that are predominantly metabolized by CYP2D6 and particularly those with a narrow therapeutic index.”
Check it at the source: the carvedilol FDA label on DailyMed (effective July 31, 2026, Waylis Therapeutics LLC); the cinacalcet FDA label on DailyMed (effective April 2, 2026, Aurobindo Pharma Limited).
What does the carvedilol label say about cinacalcet?
Carvedilol's label (effective July 31, 2026) and its 1 other brand-application label do not name cinacalcet in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Coreg), Waylis Therapeutics LLC, effective July 31, 2026 (SPL set 07c619c6-4a0c-445e-94fa-664a54f68a39), via openFDA; the full label on DailyMed
What does the cinacalcet label say about carvedilol?
Cinacalcet label, drug interactionsDose adjustments may be required for concomitant medications that are predominantly metabolized by CYP2D6 (e.g., desipramine, metoprolol, and carvedilol) and particularly those with a narrow therapeutic index (e.g., flecainide and most tricyclic antidepressants) [see Clinical Pharmacology (12.3) ].
Source: FDA drug label (Cinacalcet), Aurobindo Pharma Limited, effective April 2, 2026 (SPL set 200390f2-7dad-4ecc-a086-c29e18525c01), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Carvedilol | Cinacalcet | |
|---|---|---|
| Labeled for | Heart failure, High blood pressure | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0179 per tablet 6.25 mg tablet | $0.411 per tablet 30 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once