Cimetidine · more major-labeled pairs than Carvedilol
SPL labels Carvedilol + Cimetidine as minor; Carvedilol 12 / Cimetidine 63 in that band.
Mechanism on file: Cimetidine interferes with how your body processes carvedilol, causing the total amount of carvedilol in your blood to increase by about 30%.
FDA SPL severity: Minor
Carvedilol + Cimetidine · SPL mechanism field
Cimetidine interferes with how your body processes carvedilol, causing the total amount of carvedilol in your blood to increase by about 30%.
Minor band excerpt · Carvedilol with Cimetidine
Cimetidine increased AUC by about 30% but caused no change in C max [see Clinical Pharmacology ( 12.5 )] .
Carvedilol · 12 minor + 13 total pairs
- Amiodarone minor
- Cyclosporine minor
- Darunavir minor
- Digoxin minor
Cimetidine · 4 major-labeled pairs (vs Carvedilol's 0)
- Albendazole minor
- Alogliptin minor
- Alosetron minor
- Alprazolam minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.