Skip to main content

What the FDA labels say about taking them together

Carmustine and cimetidine

Carmustine's FDA label of April 9, 2026 names cimetidine in its drug interactions section; the cimetidine label PlainMeds reads does not name carmustine. The carmustine label: “DRUG INTERACTIONS Cimetidine: Increased myelosuppression with concomitant use. Phenobarbital: Induces carmustine metabolism, reducing exposure.”

Check it at the source: the carmustine FDA label on DailyMed (effective April 9, 2026, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.); the cimetidine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.).

What does the carmustine label say about cimetidine?

Carmustine label, drug interactions

DRUG INTERACTIONS Cimetidine: Increased myelosuppression with concomitant use. (7.1) Phenobarbital: Induces carmustine metabolism, reducing exposure.

Carmustine label, warnings and precautions

Greater myelotoxicity (e.g., leukopenia and neutropenia) has been reported when carmustine was combined with cimetidine [see Drug Interactions (7) ].

Source: FDA drug label (CARMUSTINE), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective April 9, 2026 (SPL set b9b47082-32ee-4abb-a7b2-52292894d3f8), via openFDA; the full label on DailyMed

What does the cimetidine label say about carmustine?

Cimetidine's label (effective July 15, 2026) does not name carmustine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Cimetidine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set 06c0a509-026f-44e0-9975-a94a8de51d43), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

10Carmustine generic labelers
18Cimetidine generic labelers
CarmustineCimetidine
Labeled forLeukemia, lymphoma and myelomaAcid reflux and ulcers
Boxed warningYesNo
Pharmacy cost (NADAC)n/a$0.236 per tablet 300 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?