What the FDA labels say about taking them together
Cannabidiol and theophylline
Cannabidiol's FDA label of May 29, 2026 names theophylline in its drug interactions section; the theophylline label PlainMeds reads does not name cannabidiol. The cannabidiol label: “Increases in exposure of certain CYP1A2 substrates may be observed when concomitantly used with EPIDIOLEX.”
Check it at the source: the cannabidiol FDA label on DailyMed (effective May 29, 2026, Jazz Pharmaceuticals, Inc.); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).
What does the cannabidiol label say about theophylline?
Cannabidiol label, drug interactionsIncreases in exposure of certain CYP1A2 substrates (e.g., theophylline, tizanidine) may be observed when concomitantly used with EPIDIOLEX.
Source: FDA drug label (Epidiolex), Jazz Pharmaceuticals, Inc., effective May 29, 2026 (SPL set 8bf27097-4870-43fb-94f0-f3d0871d1eec), via openFDA; the full label on DailyMed
What does the theophylline label say about cannabidiol?
Theophylline's label (effective March 10, 2026) does not name cannabidiol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cannabidiol | Theophylline | |
|---|---|---|
| Labeled for | n/a | Asthma |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.330 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once