What the FDA labels say about taking them together
Cangrelor and clopidogrel
Cangrelor's FDA label of October 21, 2025 names clopidogrel in its drug interactions section; the clopidogrel label PlainMeds reads does not name cangrelor. The cangrelor label: “DRUG INTERACTIONS Clopidogrel: Do not administer during KENGREAL infusion.”
Check it at the source: the cangrelor FDA label on DailyMed (effective October 21, 2025, Chiesi USA, Inc.); the clopidogrel FDA label on DailyMed (effective May 30, 2025, Sanofi-Aventis U.S. LLC).
What does the cangrelor label say about clopidogrel?
Cangrelor label, drug interactionsDRUG INTERACTIONS Clopidogrel: Do not administer during KENGREAL infusion.
Cangrelor label, warnings and precautionsIn CHAMPION PHOENIX bleeding events of all severities were more common with KENGREAL than with clopidogrel [see Adverse Reactions ( 6.1 )].
Source: FDA drug label (KENGREAL), Chiesi USA, Inc., effective October 21, 2025 (SPL set 88b434fa-8891-4fd5-9d86-7ea64667c08f), via openFDA; the full label on DailyMed
What does the clopidogrel label say about cangrelor?
Clopidogrel's label (effective May 30, 2025) does not name cangrelor in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Plavix), Sanofi-Aventis U.S. LLC, effective May 30, 2025 (SPL set de8b0b67-eb25-4684-83b5-7ad785314227), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cangrelor | Clopidogrel | |
|---|---|---|
| Labeled for | Heart attack and coronary artery disease | Heart attack and coronary artery disease, Angina |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.0472 per tablet 75 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once