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What the FDA labels say about taking them together

Candesartan and lithium

Candesartan's FDA label of January 15, 2026 names lithium in its drug interactions section; the lithium labels PlainMeds reads (4) do not name candesartan. The candesartan label: “DRUG INTERACTIONS Lithium: Increases in serum lithium concentrations and toxicity.”

Check it at the source: the candesartan FDA label on DailyMed (effective January 15, 2026, Golden State Medical Supply, Inc.); the lithium FDA label on DailyMed (effective December 23, 2025, Glenmark Pharmaceuticals Inc., USA).

What does the candesartan label say about lithium?

Candesartan label, drug interactions

DRUG INTERACTIONS Lithium: Increases in serum lithium concentrations and toxicity ( 7 ).

Source: FDA drug label (Candesartan cilexetil), NDA020838 (Ani Pharms), as published by Golden State Medical Supply, Inc., effective January 15, 2026 (SPL set 15601654-76da-04cf-e063-6394a90a2cb5), via openFDA; the full label on DailyMed

What does the lithium label say about candesartan?

Lithium's label (effective December 23, 2025) and its 3 other brand-application labels do not name candesartan in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Lithium Carbonate), Glenmark Pharmaceuticals Inc., USA, effective December 23, 2025 (SPL set 63b3790f-a9b5-47f4-bae1-ddf8b43c13c1), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

8Candesartan generic labelers
24Lithium generic labelers
CandesartanLithium
Labeled forHigh blood pressure, Heart failureBipolar disorder
Boxed warningYesYes
Pharmacy cost (NADAC)$0.478 per tablet 16 mg tablet$0.104 per capsule 300 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?