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What the FDA labels say about taking them together

Calcitriol and ferric oxyhydroxide

Ferric oxyhydroxide's FDA label of April 1, 2026 names calcitriol in its drug interactions section; the calcitriol labels PlainMeds reads (3) do not name ferric oxyhydroxide.

Check it at the source: the calcitriol FDA label on DailyMed (effective October 23, 2024, Amneal Pharmaceuticals LLC); the ferric oxyhydroxide FDA label on DailyMed (effective April 1, 2026, Fresenius Medical Care Renal Therapies Group, LLC).

What does the calcitriol label say about ferric oxyhydroxide?

Calcitriol's label (effective October 23, 2024) and its 2 other brand-application labels do not name ferric oxyhydroxide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Calcitriol), Amneal Pharmaceuticals LLC, effective October 23, 2024 (SPL set b1fef137-63c5-4662-8cd9-b9e8b12bacb6), via openFDA; the full label on DailyMed

What does the ferric oxyhydroxide label say about calcitriol?

Ferric oxyhydroxide label, drug interactions

DRUG INTERACTIONS Table 1 Oral drugs that can be administered concomitantly with Velphoro Calcitriol Ciprofloxacin Digoxin Enalapril Furosemide HMG-CoA reductase inhibitors Hydrochlorothiazide Losartan Metoprolol Nifedipine Omeprazole Quinidine Warfarin Oral drugs that are to be separated from Velphoro Dosing Recommendations Doxycycline Acetylsalicylic acid Cephalexin Take at least 1 hour before Velphoro.

Source: FDA drug label (Velphoro), Fresenius Medical Care Renal Therapies Group, LLC, effective April 1, 2026 (SPL set 237da26c-f38c-4faa-93ad-735e71c9d0c1), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

20Calcitriol generic labelers
0Ferric oxyhydroxide generic labelers
CalcitriolFerric oxyhydroxide
Labeled forPsoriasisn/a
Boxed warningNoNo
Pharmacy cost (NADAC)$0.153 per capsule 0.25 mcg capsule$17.11 per tablet 500 mg chewable tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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