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What the FDA labels say about taking them together

Calcitriol and cholestyramine

Calcitriol's FDA label (Calcitriol) of July 10, 2026 names cholestyramine in its drug interactions section; the cholestyramine label PlainMeds reads does not name calcitriol. The calcitriol label: “DRUG INTERACTIONS Cholestyramine Cholestyramine has been reported to reduce intestinal absorption of fat-soluble vitamins; as such it may impair intestinal absorption of calcitriol (see WARNINGS and PRECAUTIONS:”

Check it at the source: the calcitriol FDA label on DailyMed (effective October 23, 2024, Amneal Pharmaceuticals LLC); the cholestyramine FDA label on DailyMed (effective August 20, 2026, AiPing Pharmaceutical, Inc.).

What does the calcitriol label say about cholestyramine?

Calcitriol label (ANI Pharmaceuticals, Inc., July 10, 2026), drug interactions

DRUG INTERACTIONS Cholestyramine Cholestyramine has been reported to reduce intestinal absorption of fat-soluble vitamins; as such it may impair intestinal absorption of calcitriol (see WARNINGS and PRECAUTIONS:

Source: FDA drug label (Calcitriol, NDA021068), ANI Pharmaceuticals, Inc., effective July 10, 2026 (SPL set bdb9c0d4-bdb3-4174-a4d9-55c423f38476), via openFDA

Source: FDA drug label (Calcitriol), Amneal Pharmaceuticals LLC, effective October 23, 2024 (SPL set b1fef137-63c5-4662-8cd9-b9e8b12bacb6), via openFDA; the full label on DailyMed

What does the cholestyramine label say about calcitriol?

Cholestyramine's label (effective August 20, 2026) does not name calcitriol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Cholestyramine), AiPing Pharmaceutical, Inc., effective August 20, 2026 (SPL set 214ea05f-de81-4026-9df9-4ce3820668ee), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

20Calcitriol generic labelers
15Cholestyramine generic labelers
CalcitriolCholestyramine
Labeled forPsoriasisHigh cholesterol
Boxed warningNoNo
Pharmacy cost (NADAC)$0.153 per capsule 0.25 mcg capsule$0.834 per packet Cholestyramine packet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?