What the FDA labels say about taking them together
Caffeine and migalastat
Migalastat's FDA label of August 28, 2025 names caffeine in its drug interactions section; the caffeine labels PlainMeds reads (2) do not name migalastat. The migalastat label: “Drugs on GALAFOLD Co-administration of GALAFOLD with caffeine decreases migalastat AUC and C max which may reduce GALAFOLD efficacy.”
Check it at the source: the caffeine FDA label on DailyMed (effective July 29, 2026, Sagent Pharmaceuticals); the migalastat FDA label on DailyMed (effective August 28, 2025, Amicus Therapeutics US, LLC).
What does the caffeine label say about migalastat?
Caffeine's label (effective July 29, 2026) and its 1 other brand-application label do not name migalastat in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (caffeine citrate), Sagent Pharmaceuticals, effective July 29, 2026 (SPL set 5f38c395-0093-4afd-89ec-f96e5dc0934a), via openFDA; the full label on DailyMed
What does the migalastat label say about caffeine?
Migalastat label, drug interactionsDrugs on GALAFOLD Co-administration of GALAFOLD with caffeine decreases migalastat AUC and C max [see Clinical Pharmacology (12.3) ] which may reduce GALAFOLD efficacy.
Source: FDA drug label (Galafold), Amicus Therapeutics US, LLC, effective August 28, 2025 (SPL set 66dbd928-0f1c-48b1-a832-54e4abd9f1db), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Caffeine | Migalastat | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.083 per tablet 200 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once