What the FDA labels say about taking them together
Caffeine and deferasirox
Deferasirox's FDA label of January 28, 2026 names caffeine in its drug interactions section; the caffeine labels PlainMeds reads (2) do not name deferasirox. The deferasirox label: “Metabolized by CYP1A2 Deferasirox inhibits CYP1A2 resulting in an increase in CYP1A2 substrate concentration when these drugs are coadministered.”
Check it at the source: the caffeine FDA label on DailyMed (effective July 29, 2026, Sagent Pharmaceuticals); the deferasirox FDA label on DailyMed (effective January 28, 2026, Novartis Pharmaceuticals Corporation).
What does the caffeine label say about deferasirox?
Caffeine's label (effective July 29, 2026) and its 1 other brand-application label do not name deferasirox in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (caffeine citrate), Sagent Pharmaceuticals, effective July 29, 2026 (SPL set 5f38c395-0093-4afd-89ec-f96e5dc0934a), via openFDA; the full label on DailyMed
What does the deferasirox label say about caffeine?
Deferasirox label, drug interactionsMetabolized by CYP1A2 Deferasirox inhibits CYP1A2 resulting in an increase in CYP1A2 substrate (e.g., alosetron, caffeine, duloxetine, melatonin, ramelteon, tacrine, theophylline, tizanidine) concentration when these drugs are coadministered.
Source: FDA drug label (Exjade), Novartis Pharmaceuticals Corporation, effective January 28, 2026 (SPL set 3495a70c-870c-4968-940e-8baea152cf85), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Caffeine | Deferasirox | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.083 per tablet 200 mg tablet | $1.25 per tablet 360 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once