What the FDA labels say about taking them together
Cabotegravir and magnesium hydroxide
Cabotegravir's FDA label (Vocabria) of April 11, 2025 names magnesium hydroxide in its drug interactions section; the magnesium hydroxide label PlainMeds reads does not name cabotegravir.
Check it at the source: the cabotegravir FDA label on DailyMed (effective April 11, 2025, ViiV Healthcare Company); the magnesium hydroxide FDA label on DailyMed (effective August 21, 2026).
What does the cabotegravir label say about magnesium hydroxide?
Vocabria label (ViiV Healthcare Company, April 11, 2025), drug interactionsConcomitant Drug Class/Drug Name: Antacids containing polyvalent cations (e.g., aluminum or magnesium hydroxide, calcium carbonate); Effect on Concentration: ↓Cabotegravir; Clinical Comment: Administer antacid products at least 2 hours before or 4 hours after taking VOCABRIA.
Source: FDA drug label (Vocabria, NDA212887), ViiV Healthcare Company, effective April 11, 2025 (SPL set 66d450fb-cca4-476c-b0c7-c0730e3e4cf3), via openFDA
Source: FDA drug label (Apretude), ViiV Healthcare Company, effective April 11, 2025 (SPL set 4338428e-43d4-4e02-ac9d-bd98e738a7da), via openFDA; the full label on DailyMed
What does the magnesium hydroxide label say about cabotegravir?
Magnesium hydroxide's label (effective August 21, 2026) does not name cabotegravir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (MiraFAST soft chews), Bayer HealthCare LLC., effective August 21, 2026 (SPL set 2cee67dd-b71f-32b8-e063-6394a90ae864), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cabotegravir | Magnesium hydroxide | |
|---|---|---|
| Labeled for | HIV | Constipation, Acid reflux and ulcers |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $0.0095 per mL Milk of magnesia suspension |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once