What the FDA labels say about taking them together
Cabotegravir and calcium carbonate
Cabotegravir's FDA label (Vocabria) of April 11, 2025 names calcium carbonate in its drug interactions section; the calcium carbonate label PlainMeds reads does not name cabotegravir.
Check it at the source: the cabotegravir FDA label on DailyMed (effective April 11, 2025, ViiV Healthcare Company); the calcium carbonate FDA label on DailyMed (effective December 5, 2024).
What does the cabotegravir label say about calcium carbonate?
Vocabria label (ViiV Healthcare Company, April 11, 2025), drug interactionsConcomitant Drug Class/Drug Name: Antacids containing polyvalent cations (e.g., aluminum or magnesium hydroxide, calcium carbonate); Effect on Concentration: ↓Cabotegravir; Clinical Comment: Administer antacid products at least 2 hours before or 4 hours after taking VOCABRIA.
Source: FDA drug label (Vocabria, NDA212887), ViiV Healthcare Company, effective April 11, 2025 (SPL set 66d450fb-cca4-476c-b0c7-c0730e3e4cf3), via openFDA
Source: FDA drug label (Apretude), ViiV Healthcare Company, effective April 11, 2025 (SPL set 4338428e-43d4-4e02-ac9d-bd98e738a7da), via openFDA; the full label on DailyMed
What does the calcium carbonate label say about cabotegravir?
Calcium carbonate's label (effective December 5, 2024) does not name cabotegravir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (TUMS EX), Haleon US Holdings LLC, effective December 5, 2024 (SPL set 593a0494-d669-4bcf-8412-b92645b2d76c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cabotegravir | Calcium carbonate | |
|---|---|---|
| Labeled for | HIV | Acid reflux and ulcers |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $0.0315 per tablet 750 mg tablet chewable |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once