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What the FDA labels say about taking them together

Cabazitaxel and ketoconazole

Cabazitaxel's FDA label of October 7, 2025 names ketoconazole in its drug interactions section; the ketoconazole label PlainMeds reads does not name cabazitaxel. The cabazitaxel label: “Strong CYP3A inhibitors may increase plasma concentrations of cabazitaxel.”

Check it at the source: the cabazitaxel FDA label on DailyMed (effective October 7, 2025, Sanofi-Aventis U.S. LLC); the ketoconazole FDA label on DailyMed (effective January 28, 2026, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC).

What does the cabazitaxel label say about ketoconazole?

Cabazitaxel label, drug interactions

Strong CYP3A inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, atazanavir, indinavir, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, voriconazole) may increase plasma concentrations of cabazitaxel.

Source: FDA drug label (Jevtana), Sanofi-Aventis U.S. LLC, effective October 7, 2025 (SPL set de3d9c26-572b-4ea4-9b2d-dd58a2b3e8fa), via openFDA; the full label on DailyMed

What does the ketoconazole label say about cabazitaxel?

Ketoconazole's label (effective January 28, 2026) does not name cabazitaxel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (ketoconazole), E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, effective January 28, 2026 (SPL set cad7c647-34a9-4e4e-83b3-8d78e58f588f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Cabazitaxel generic labelers
30Ketoconazole generic labelers
CabazitaxelKetoconazole
Labeled forProstate cancerFungal infections
Boxed warningYesNo
Pharmacy cost (NADAC)n/a$0.249 per gram 2% cream
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?