What the FDA labels say about taking them together
Busulfan and deferasirox
Busulfan's FDA label of June 27, 2024 names deferasirox in its drug interactions section, and deferasirox's label names busulfan too. The busulfan label: “Decreased clearance of busulfan was observed with concomitant use with deferasirox.”
Check it at the source: the busulfan FDA label on DailyMed (effective June 27, 2024, Eugia US LLC); the deferasirox FDA label on DailyMed (effective January 28, 2026, Novartis Pharmaceuticals Corporation).
What does the busulfan label say about deferasirox?
Busulfan label, drug interactionsDecreased clearance of busulfan was observed with concomitant use with deferasirox.
Source: FDA drug label (Busulfan), Eugia US LLC, effective June 27, 2024 (SPL set 06883ac0-4b2a-4f26-89bf-512d37b9ba7f), via openFDA; the full label on DailyMed
What does the deferasirox label say about busulfan?
Deferasirox label, drug interactionsConsider repaglinide dose reduction and monitor blood glucose levels. ( 7.3 ) Avoid the use of Exjade with CYP1A2 substrate theophylline. ( 7.4 ) Deferasirox increases exposure of busulfan.
Source: FDA drug label (Jadenu, NDA206910), Novartis Pharmaceuticals Corporation, effective December 11, 2025 (SPL set fee89140-fff1-4443-9f42-24ac004fcda1), via openFDA
Source: FDA drug label (Exjade), Novartis Pharmaceuticals Corporation, effective January 28, 2026 (SPL set 3495a70c-870c-4968-940e-8baea152cf85), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Busulfan | Deferasirox | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | $1.25 per tablet 360 mg tablet |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once