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What the FDA labels say about taking them together

Bromocriptine and chloramphenicol

Bromocriptine's FDA label (Cycloset) of January 12, 2026 names chloramphenicol in its drug interactions section; the chloramphenicol label PlainMeds reads does not name bromocriptine. The bromocriptine label: “Therefore, CYCLOSET may increase the unbound fraction of other concomitantly used highly protein-bound therapies, which may alter their effectiveness and risk for side effects.”

Check it at the source: the bromocriptine FDA label on DailyMed (effective July 27, 2026, ANI Pharmaceuticals, Inc.); the chloramphenicol FDA label on DailyMed (effective October 10, 2024, Fresenius Kabi USA, LLC).

What does the bromocriptine label say about chloramphenicol?

Cycloset label (Avvisto Therapeutics LLC, January 12, 2026), drug interactions

Therefore, CYCLOSET may increase the unbound fraction of other concomitantly used highly protein-bound therapies (e.g., salicylates, sulfonamides, chloramphenicol and probenecid), which may alter their effectiveness and risk for side effects.

Source: FDA drug label (Cycloset, NDA020866), Avvisto Therapeutics LLC, effective January 12, 2026 (SPL set e42ba916-16b9-4d1c-8d09-9d2fbb1b6c20), via openFDA

Source: FDA drug label (Bromocriptine Mesylate), ANI Pharmaceuticals, Inc., effective July 27, 2026 (SPL set 17f3a343-1782-4799-95ba-31dfe93be2cf), via openFDA; the full label on DailyMed

What does the chloramphenicol label say about bromocriptine?

Chloramphenicol's label (effective October 10, 2024) does not name bromocriptine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Chloramphenicol Sodium Succinate), Fresenius Kabi USA, LLC, effective October 10, 2024 (SPL set aed29594-211d-49ef-813f-131975a8d0e3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

6Bromocriptine generic labelers
1Chloramphenicol generic labelers
BromocriptineChloramphenicol
Labeled forParkinson's disease, Type 2 diabetesn/a
Boxed warningNoYes
Pharmacy cost (NADAC)$1.61 per tablet 2.5 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?