What the FDA labels say about taking them together
Brodalumab and ustekinumab
Brodalumab's FDA label of May 28, 2026 names ustekinumab in its warnings and precautions section; the ustekinumab labels PlainMeds reads (4) do not name brodalumab. The brodalumab label: “During the course of clinical trials for plaque psoriasis, the exposure-adjusted rates for infections and serious infections were similar in the subjects treated with SILIQ and those treated with ustekinumab.”
Check it at the source: the brodalumab FDA label on DailyMed (effective May 28, 2026, Bausch Health US LLC); the ustekinumab FDA label on DailyMed (effective September 8, 2026, Janssen Biotech, Inc.).
What does the brodalumab label say about ustekinumab?
Brodalumab label, warnings and precautionsDuring the course of clinical trials for plaque psoriasis, the exposure-adjusted rates for infections and serious infections were similar in the subjects treated with SILIQ and those treated with ustekinumab.
Source: FDA drug label (Siliq), BLA761032 (Valeant Luxembourg), as published by Bausch Health US LLC, effective May 28, 2026 (SPL set 1a550c33-456a-4833-814e-8591aea7c688), via openFDA; the full label on DailyMed
What does the ustekinumab label say about brodalumab?
Ustekinumab's label (effective September 8, 2026) and its 3 other brand-application labels do not name brodalumab in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Stelara), Janssen Biotech, Inc., effective September 8, 2026 (SPL set c77a9664-e3bb-4023-b400-127aa53bca2b), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Brodalumab | Ustekinumab | |
|---|---|---|
| Labeled for | Psoriasis | Crohn's disease and ulcerative colitis |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $29,874.45 per mL 45 mg/0.5 mL syringe |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once