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What the FDA labels say about taking them together

Brivaracetam and rifampin

Brivaracetam's FDA label of August 20, 2026 names rifampin in its drug interactions section; the rifampin label PlainMeds reads does not name brivaracetam. The brivaracetam label: “DRUG INTERACTIONS Rifampin: Because of decreased concentrations, increasing BRIVIACT dosage in patients on concomitant rifampin is recommended.”

Check it at the source: the brivaracetam FDA label on DailyMed (effective August 20, 2026, UCB, Inc.); the rifampin FDA label on DailyMed (effective February 11, 2026, Lupin Pharmaceuticals, Inc.).

What does the brivaracetam label say about rifampin?

Brivaracetam label, drug interactions

DRUG INTERACTIONS Rifampin: Because of decreased concentrations, increasing BRIVIACT dosage in patients on concomitant rifampin is recommended.

Source: FDA drug label (Briviact), NDA205836 (Ucb Inc), as published by UCB, Inc., effective August 20, 2026 (SPL set 3cf2f439-0e97-443e-8e33-25ecef616f6c), via openFDA; the full label on DailyMed

What does the rifampin label say about brivaracetam?

Rifampin's label (effective February 11, 2026) does not name brivaracetam in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (rifampin), Lupin Pharmaceuticals, Inc., effective February 11, 2026 (SPL set b56004f0-f23d-47f6-80c7-39884fccbccc), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

16Brivaracetam generic labelers
13Rifampin generic labelers
BrivaracetamRifampin
Labeled forSeizures and epilepsyn/a
Boxed warningNoNo
Pharmacy cost (NADAC)$0.259 per tablet 100 mg tablet$0.679 per capsule 300 mg capsule
Shortage nowNo current entryIn shortage

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?