What the FDA labels say about taking them together
Bortezomib and venetoclax
Venetoclax's FDA label of May 20, 2026 names bortezomib in its warnings and precautions section; the bortezomib labels PlainMeds reads (4) do not name venetoclax. The venetoclax label: “… Treatment of patients with multiple myeloma with VENCLEXTA in combination with bortezomib plus dexamethasone is not recommended outside of controlled clinical trials.”
Check it at the source: the bortezomib FDA label on DailyMed (effective February 27, 2023, Hospira, Inc.); the venetoclax FDA label on DailyMed (effective May 20, 2026, AbbVie Inc.).
What does the bortezomib label say about venetoclax?
Bortezomib's label (effective February 27, 2023) and its 3 other brand-application labels do not name venetoclax in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (BORTEZOMIB), Hospira, Inc., effective February 27, 2023 (SPL set 9fdf6169-699f-40eb-bda1-760253062b3c), via openFDA; the full label on DailyMed
What does the venetoclax label say about bortezomib?
Venetoclax label, warnings and precautionsAdvise females of reproductive potential of the potential risk to a fetus and to use effective contraception. ( 5.5 ) Treatment of patients with multiple myeloma with VENCLEXTA in combination with bortezomib plus dexamethasone is not recommended outside of controlled clinical trials.
Source: FDA drug label (Venclexta), AbbVie Inc., effective May 20, 2026 (SPL set b118a40d-6b56-cee3-10f6-ded821a97018), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Bortezomib | Venetoclax | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | Leukemia, lymphoma and myeloma |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once