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What the FDA labels say about taking them together

Bortezomib and thalidomide

Thalidomide's FDA label of March 24, 2023 names bortezomib in its drug interactions section; the bortezomib labels PlainMeds reads (4) do not name thalidomide.

Check it at the source: the bortezomib FDA label on DailyMed (effective February 27, 2023, Hospira, Inc.); the thalidomide FDA label on DailyMed (effective March 24, 2023, Celgene Corporation).

What does the bortezomib label say about thalidomide?

Bortezomib's label (effective February 27, 2023) and its 3 other brand-application labels do not name thalidomide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (BORTEZOMIB), Hospira, Inc., effective February 27, 2023 (SPL set 9fdf6169-699f-40eb-bda1-760253062b3c), via openFDA; the full label on DailyMed

What does the thalidomide label say about bortezomib?

Thalidomide label, drug interactions

Drugs which Cause Peripheral Neuropathy The use of drugs which cause peripheral neuropathy (e.g., bortezomib, amiodarone, cisplatin, docetaxel, paclitaxel, vincristine, disulfiram, phenytoin, metronidazole, alcohol) can cause an additive effect and should be used with caution.

Source: FDA drug label (Thalomid), NDA020785 (Bristol-Myers), as published by Celgene Corporation, effective March 24, 2023 (SPL set 2eda833b-1357-4ed4-a093-194524fcb061), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

22Bortezomib generic labelers
0Thalidomide generic labelers
BortezomibThalidomide
Labeled forLeukemia, lymphoma and myelomaLeukemia, lymphoma and myeloma
Boxed warningNoYes
Pharmacy cost (NADAC)n/an/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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