What the FDA labels say about taking them together
Bisoprolol and disopyramide
Bisoprolol's FDA label of March 11, 2026 names disopyramide in its drug interactions section; the disopyramide label PlainMeds reads does not name bisoprolol.
Check it at the source: the bisoprolol FDA label on DailyMed (effective March 11, 2026, Micro Labs Limited); the disopyramide FDA label on DailyMed (effective August 24, 2026, Pfizer Laboratories Div Pfizer Inc).
What does the bisoprolol label say about disopyramide?
Bisoprolol label, drug interactionsBisoprolol fumarate should be used with care when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently.
Source: FDA drug label (Bisoprolol), Micro Labs Limited, effective March 11, 2026 (SPL set c3ee566c-74c4-45f4-a947-526a7313e326), via openFDA; the full label on DailyMed
What does the disopyramide label say about bisoprolol?
Disopyramide's label (effective August 24, 2026) does not name bisoprolol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Norpace), Pfizer Laboratories Div Pfizer Inc, effective August 24, 2026 (SPL set e2aa1642-d262-4520-bc6a-9fd3ad795677), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Bisoprolol | Disopyramide | |
|---|---|---|
| Labeled for | High blood pressure | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.114 per tablet 5 mg tablet | $0.801 per capsule 100 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once