What the FDA labels say about taking them together
Bisacodyl and polyethylene glycol 3350, potassium chloride, sodium bicarbonate and sodium chloride
Polyethylene glycol 3350, potassium chloride, sodium bicarbonate and sodium chloride's FDA label of April 14, 2026 names bisacodyl in its drug interactions section; the bisacodyl label PlainMeds reads does not name polyethylene glycol 3350, potassium chloride, sodium bicarbonate and sodium chloride. The polyethylene glycol 3350, potassium chloride, sodium bicarbonate and sodium chloride label: “Avoid use of stimulant laxatives while taking PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride for oral solution.”
Check it at the source: the bisacodyl FDA label on DailyMed (effective April 8, 2025); the polyethylene glycol 3350, potassium chloride, sodium bicarbonate and sodium chloride FDA label on DailyMed (effective April 14, 2026, Wilshire Pharmaceuticals, Inc.).
What does the bisacodyl label say about polyethylene glycol 3350, potassium chloride, sodium bicarbonate and sodium chloride?
Bisacodyl's label (effective April 8, 2025) does not name polyethylene glycol 3350, potassium chloride, sodium bicarbonate and sodium chloride in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Dulcolax Stimulant Laxative), Chattem, Inc., effective April 8, 2025 (SPL set f1e4b28a-ed74-4eff-bd10-b2bfaf7483b0), via openFDA; the full label on DailyMed
What does the polyethylene glycol 3350, potassium chloride, sodium bicarbonate and sodium chloride label say about bisacodyl?
Polyethylene glycol 3350, potassium chloride, sodium bicarbonate and sodium chloride label, drug interactionsAvoid use of stimulant laxatives (e.g., bisacodyl, sodium picosulfate) while taking PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride for oral solution.
Source: FDA drug label (PEG 3350, sodium chloride, sodium bicarbonate and potassium chloride), NDA019797 (Azurity), as published by Wilshire Pharmaceuticals, Inc., effective April 14, 2026 (SPL set 4e442a72-b13b-4869-8a1d-59356095b091), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Bisacodyl | Polyethylene glycol 3350, potassium chloride, sodium bicarbonate and sodium chloride | |
|---|---|---|
| Labeled for | Constipation | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.320 per suppository 10 mg suppository | $0.0046 per mL 3350-electrolyte solution |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once