What the FDA labels say about taking them together
Bimekizumab and cyclosporine
Bimekizumab's FDA label of June 16, 2025 names cyclosporine in its drug interactions section; the cyclosporine labels PlainMeds reads (4) do not name bimekizumab. The bimekizumab label: “… monitoring for effect (e.g., for warfarin) or drug concentration (e.g., for cyclosporine) and consider dosage modification of the CYP450 substrate.”
Check it at the source: the bimekizumab FDA label on DailyMed (effective June 16, 2025); the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation).
What does the bimekizumab label say about cyclosporine?
Bimekizumab label, drug interactionsTherefore, upon initiation or discontinuation of BIMZELX in patients who are receiving concomitant drugs which are CYP450 substrates, particularly those with a narrow therapeutic index, consider monitoring for effect (e.g., for warfarin) or drug concentration (e.g., for cyclosporine) and consider dosage modification of the CYP450 substrate.
Source: FDA drug label (Bimzelx), UCB, Inc., effective June 16, 2025 (SPL set 26b88358-871f-4c80-9d80-b2fb16477f81), via openFDA; the full label on DailyMed
What does the cyclosporine label say about bimekizumab?
Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name bimekizumab in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Bimekizumab | Cyclosporine | |
|---|---|---|
| Labeled for | Psoriasis | Organ transplant rejection, Rheumatoid arthritis |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $8,073.83 per mL 160 mg/mL autoinjector | $1.04 per unit 0.05% eye emulsion |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once