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What the FDA labels say about taking them together

Bexarotene and vitamin a

Bexarotene's FDA label of April 30, 2020 names vitamin a in its warnings and precautions section; the vitamin a label PlainMeds reads does not name bexarotene. The bexarotene label: “Because of the relationship of bexarotene to vitamin A, patients should be advised to limit vitamin A supplements to avoid potential additive toxic effects.”

Check it at the source: the bexarotene FDA label on DailyMed (effective April 30, 2020, Bausch Health US, LLC); the vitamin a FDA label on DailyMed (effective March 3, 2026, Rising Pharma Holdings, Inc.).

What does the bexarotene label say about vitamin a?

Bexarotene label, warnings and precautions

Because of the relationship of bexarotene to vitamin A, patients should be advised to limit vitamin A supplements to avoid potential additive toxic effects.

Source: FDA drug label (Targretin), Bausch Health US, LLC, effective April 30, 2020 (SPL set 1d056725-0576-4338-8089-6336e768ccdc), via openFDA; the full label on DailyMed

What does the vitamin a label say about bexarotene?

Vitamin a's label (effective March 3, 2026) does not name bexarotene in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (AQUASOL A Parenteral), Rising Pharma Holdings, Inc., effective March 3, 2026 (SPL set 1abd66eb-6ac8-4a9e-a609-251e46ea1a27), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

7Bexarotene generic labelers
0Vitamin a generic labelers
BexaroteneVitamin a
Labeled forLeukemia, lymphoma and myeloman/a
Boxed warningYesNo
Pharmacy cost (NADAC)n/an/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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