What the FDA labels say about taking them together
Bexagliflozin and lithium
Bexagliflozin's FDA label of June 23, 2026 names lithium in its drug interactions section; the lithium labels PlainMeds reads (4) do not name bexagliflozin. The bexagliflozin label: “Lithium Clinical Impact Concomitant use with SGLT2 inhibitors such as bexagliflozin tablets may decrease serum lithium concentrations. …”
Check it at the source: the bexagliflozin FDA label on DailyMed (effective June 23, 2026, TheracosBio, LLC); the lithium FDA label on DailyMed (effective December 23, 2025, Glenmark Pharmaceuticals Inc., USA).
What does the bexagliflozin label say about lithium?
Bexagliflozin label, drug interactionsLithium Clinical Impact Concomitant use with SGLT2 inhibitors such as bexagliflozin tablets may decrease serum lithium concentrations. Intervention Monitor serum lithium concentration more frequently upon bexagliflozin tablets initiation and discontinuation.
Source: FDA drug label (Bexagliflozin), TheracosBio, LLC, effective June 23, 2026 (SPL set 7f0ad5d2-3509-4057-904c-d27993de7408), via openFDA; the full label on DailyMed
What does the lithium label say about bexagliflozin?
Lithium's label (effective December 23, 2025) and its 3 other brand-application labels do not name bexagliflozin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lithium Carbonate), Glenmark Pharmaceuticals Inc., USA, effective December 23, 2025 (SPL set 63b3790f-a9b5-47f4-bae1-ddf8b43c13c1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Bexagliflozin | Lithium | |
|---|---|---|
| Labeled for | Type 2 diabetes | Bipolar disorder |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.104 per capsule 300 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once