What the FDA labels say about taking them together
Bevacizumab and naloxegol
Naloxegol's FDA label of September 1, 2026 names bevacizumab in its warnings and precautions section; the bevacizumab labels PlainMeds reads (4) do not name naloxegol. The naloxegol label: “Postmarketing cases of GI perforation, including fatal cases, were reported when MOVANTIK was used in patients at risk of GI perforation.”
Check it at the source: the bevacizumab FDA label on DailyMed (effective March 23, 2026, Amneal Pharmaceuticals LLC); the naloxegol FDA label on DailyMed (effective September 1, 2026, Averitas Pharma, Inc.).
What does the bevacizumab label say about naloxegol?
Bevacizumab's label (effective March 23, 2026) and its 3 other brand-application labels do not name naloxegol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ALYMSYS), Amneal Pharmaceuticals LLC, effective March 23, 2026 (SPL set 6b4040a2-a5c5-4ff0-ab45-935d7e49cf78), via openFDA; the full label on DailyMed
What does the naloxegol label say about bevacizumab?
Naloxegol label, warnings and precautionsPostmarketing cases of GI perforation, including fatal cases, were reported when MOVANTIK was used in patients at risk of GI perforation (e.g., infiltrative gastrointestinal tract malignancy, recent gastrointestinal tract surgery, diverticular disease including diverticulitis, ischemic colitis, or concomitantly treated with bevacizumab).
Source: FDA drug label (MOVANTIK), Averitas Pharma, Inc., effective September 1, 2026 (SPL set 28596788-b73f-4247-85fc-3105f51fff5a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Bevacizumab | Naloxegol | |
|---|---|---|
| Labeled for | Colorectal cancer, Lung cancer | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $14.61 per tablet 25 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once