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What the FDA labels say about taking them together

Bevacizumab and epinephrine

Bevacizumab's FDA label of March 23, 2026 names epinephrine in its warnings and precautions section; the epinephrine labels PlainMeds reads (4) do not name bevacizumab.

Check it at the source: the bevacizumab FDA label on DailyMed (effective March 23, 2026, Amneal Pharmaceuticals LLC); the epinephrine FDA label on DailyMed (effective July 13, 2026, A-S Medication Solutions).

What does the bevacizumab label say about epinephrine?

Bevacizumab label, warnings and precautions

Discontinue in patients who develop a severe infusion-related reaction and administer appropriate medical therapy (e.g., epinephrine, corticosteroids, intravenous antihistamines, bronchodilators and/or oxygen).

Source: FDA drug label (ALYMSYS), Amneal Pharmaceuticals LLC, effective March 23, 2026 (SPL set 6b4040a2-a5c5-4ff0-ab45-935d7e49cf78), via openFDA; the full label on DailyMed

What does the epinephrine label say about bevacizumab?

Epinephrine's label (effective July 13, 2026) and its 3 other brand-application labels do not name bevacizumab in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Epinephrine), A-S Medication Solutions, effective July 13, 2026 (SPL set 6e811e28-0199-4df7-a916-5940c632401d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Bevacizumab generic labelers
16Epinephrine generic labelers
BevacizumabEpinephrine
Labeled forColorectal cancer, Lung cancerAsthma
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$123.51 per unit 0.15 mg auto-injct
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?