What the FDA labels say about taking them together
Benznidazole and disulfiram
Benznidazole's FDA label of August 27, 2026 names disulfiram in its contraindications section; the disulfiram label PlainMeds reads does not name benznidazole. The benznidazole label: “Tablets are contraindicated in patients who have taken disulfiram within the last two weeks.”
Check it at the source: the benznidazole FDA label on DailyMed (effective August 27, 2026, Exeltis USA, Inc.); the disulfiram FDA label on DailyMed (effective August 20, 2024, Sigmapharm Laboratories, LLC).
What does the benznidazole label say about disulfiram?
Benznidazole label, contraindicationsTablets are contraindicated in patients who have taken disulfiram within the last two weeks.
Benznidazole label, drug interactionsBenznidazole Tablets should not be given to patients who have taken disulfiram within the last two weeks [see Contraindications ( 4.2 )].
Source: FDA drug label (Benznidazole), NDA209570 (Chemo Research Sl), as published by Exeltis USA, Inc., effective August 27, 2026 (SPL set 8983d6a0-f63f-4f8e-bba4-38223f39e29b), via openFDA; the full label on DailyMed
What does the disulfiram label say about benznidazole?
Disulfiram's label (effective August 20, 2024) does not name benznidazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Disulfiram), Sigmapharm Laboratories, LLC, effective August 20, 2024 (SPL set 40f5497f-fe84-43b2-8ff4-32d59edf3917), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Benznidazole | Disulfiram | |
|---|---|---|
| Labeled for | n/a | Alcohol use disorder |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $1.82 per tablet 250 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once