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What the FDA labels say about taking them together

Benazepril/hydrochlorothiazide and epinephrine

Benazepril/hydrochlorothiazide's FDA label of February 24, 2026 names epinephrine in its warnings section; the epinephrine labels PlainMeds reads (4) do not name benazepril/hydrochlorothiazide.

Check it at the source: the benazepril/hydrochlorothiazide FDA label on DailyMed (effective February 24, 2026, Validus Pharmaceuticals LLC); the epinephrine FDA label on DailyMed (effective July 13, 2026, A-S Medication Solutions).

What does the benazepril/hydrochlorothiazide label say about epinephrine?

Benazepril/hydrochlorothiazide label, warnings

When involvement of the tongue, glottis, or larynx appears likely to cause airway obstruction, appropriate therapy, e.g., subcutaneous epinephrine injection 1:1000 (0.3 - 0.5 mL) should be promptly administered ( see PRECAUTIONS and ADVERSE REACTIONS ).

Source: FDA drug label (Lotensin HCT), Validus Pharmaceuticals LLC, effective February 24, 2026 (SPL set 94c4536f-e28e-48b1-8336-b3939917e99d), via openFDA; the full label on DailyMed

What does the epinephrine label say about benazepril/hydrochlorothiazide?

Epinephrine's label (effective July 13, 2026) and its 3 other brand-application labels do not name benazepril/hydrochlorothiazide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Epinephrine), A-S Medication Solutions, effective July 13, 2026 (SPL set 6e811e28-0199-4df7-a916-5940c632401d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

3Benazepril/hydrochlorothiazide generic labelers
16Epinephrine generic labelers
Benazepril/hydrochlorothiazideEpinephrine
Labeled forHigh blood pressureAsthma
Boxed warningYesNo
Pharmacy cost (NADAC)$0.222 per tablet 20-12.5 mg tablet$123.51 per unit 0.15 mg auto-injct
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?