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What the FDA labels say about taking them together

Belatacept and tacrolimus

Belatacept's FDA label of July 28, 2021 names tacrolimus in its warnings and precautions section; the tacrolimus labels PlainMeds reads (4) do not name belatacept.

Check it at the source: the belatacept FDA label on DailyMed (effective July 28, 2021, E.R. Squibb & Sons, L.L.C.); the tacrolimus FDA label on DailyMed (effective July 17, 2026, Stellon Biotech Inc.).

What does the belatacept label say about tacrolimus?

Belatacept label, warnings and precautions

In a clinical trial of liver transplant patients, use of NULOJIX regimens with more frequent administration of belatacept than any of those studied in kidney transplant, along with mycophenolate mofetil (MMF) and corticosteroids, was associated with a higher rate of graft loss and death compared to the tacrolimus control arms.

Source: FDA drug label (NULOJIX), E.R. Squibb & Sons, L.L.C., effective July 28, 2021 (SPL set c16ac648-d5d2-9f7d-8637-e2328572754e), via openFDA; the full label on DailyMed

What does the tacrolimus label say about belatacept?

Tacrolimus's label (effective July 17, 2026) and its 3 other brand-application labels do not name belatacept in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Tacrolimus), Stellon Biotech Inc., effective July 17, 2026 (SPL set 6b89e8a4-9f11-42e3-8e79-fe617e7c461f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Belatacept generic labelers
33Tacrolimus generic labelers
BelataceptTacrolimus
Labeled forOrgan transplant rejectionOrgan transplant rejection, Eczema (atopic dermatitis)
Boxed warningYesYes
Pharmacy cost (NADAC)n/a$0.970 per gram 0.1% ointment
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?