What the FDA labels say about taking them together
Bedaquiline and ritonavir
Ritonavir's FDA label of July 23, 2026 names bedaquiline in its drug interactions section; the bedaquiline label PlainMeds reads does not name ritonavir. The ritonavir label: “Bedaquiline should only be used with ritonavir if the benefit of co-administration outweighs the risk.”
Check it at the source: the bedaquiline FDA label on DailyMed (effective October 17, 2025, Janssen Products, LP); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the bedaquiline label say about ritonavir?
Bedaquiline's label (effective October 17, 2025) does not name ritonavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (SIRTURO), Janssen Products, LP, effective October 17, 2025 (SPL set 1534c9ae-4948-4cf4-9f66-222a99db6d0e), via openFDA; the full label on DailyMed
What does the ritonavir label say about bedaquiline?
Ritonavir label, drug interactionsConcomitant Drug Class/Drug Name: Antimycobacterial: bedaquiline; Effect on Concentration of Ritonavir or Concomitant Drug: ↑ bedaquiline; Clinical Comment: Bedaquiline should only be used with ritonavir if the benefit of co-administration outweighs the risk.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Bedaquiline | Ritonavir | |
|---|---|---|
| Labeled for | n/a | HIV |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once