What the FDA labels say about taking them together
Balsalazide and mesalamine
Balsalazide's FDA label of September 9, 2026 names mesalamine in its warnings and precautions section; the mesalamine labels PlainMeds reads (4) do not name balsalazide.
Check it at the source: the balsalazide FDA label on DailyMed (effective September 9, 2026, Apotex Corp.); the mesalamine FDA label on DailyMed (effective August 27, 2026, Salix Pharmaceuticals, Inc.).
What does the balsalazide label say about mesalamine?
Balsalazide label, warnings and precautionsUse of mesalamine may lead to spuriously elevated test results when measuring urinary normetanephrine by liquid chromatography with electrochemical detection.
Source: FDA drug label (Balsalazide Disodium), Apotex Corp., effective September 9, 2026 (SPL set f12ffa32-d14b-e9d9-e957-2ef08b64e8b4), via openFDA; the full label on DailyMed
What does the mesalamine label say about balsalazide?
Mesalamine's label (effective August 27, 2026) and its 3 other brand-application labels do not name balsalazide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (APRISO), Salix Pharmaceuticals, Inc., effective August 27, 2026 (SPL set 7951139c-b271-45a4-b523-34b23800917b), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Balsalazide | Mesalamine | |
|---|---|---|
| Labeled for | Crohn's disease and ulcerative colitis | Crohn's disease and ulcerative colitis |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.344 per capsule 750 mg capsule | $0.781 per tablet 1.2 g tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once