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What the FDA labels say about taking them together

Azithromycin and pimozide

Pimozide's FDA label of August 12, 2026 names azithromycin in its contraindications section; the azithromycin labels PlainMeds reads (4) do not name pimozide. The pimozide label: “For these reasons, pimozide is contraindicated in patients receiving the macrolide antibiotics clarithromycin, erythromycin, azithromycin, dirithromycin, and troleandomycin.”

Check it at the source: the azithromycin FDA label on DailyMed (effective December 4, 2025, Bionpharma Inc.); the pimozide FDA label on DailyMed (effective August 12, 2026, Par Health USA, LLC).

What does the azithromycin label say about pimozide?

Azithromycin's label (effective December 4, 2025) and its 3 other brand-application labels do not name pimozide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Azithromycin), Bionpharma Inc., effective December 4, 2025 (SPL set 859bb02c-a4bc-46fa-9fc9-def1219b5dfb), via openFDA; the full label on DailyMed

What does the pimozide label say about azithromycin?

Pimozide label, contraindications

For these reasons, pimozide is contraindicated in patients receiving the macrolide antibiotics clarithromycin, erythromycin, azithromycin, dirithromycin, and troleandomycin.

Source: FDA drug label (Pimozide), Par Health USA, LLC, effective August 12, 2026 (SPL set 70b079e2-a1f7-4a93-8685-d60a4d7c1280), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

55Azithromycin generic labelers
2Pimozide generic labelers
AzithromycinPimozide
Labeled forBacterial infectionsn/a
Boxed warningNoNo
Pharmacy cost (NADAC)$0.266 per tablet 250 mg tablet$1.23 per tablet 1 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?