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What the FDA labels say about taking them together

Axitinib and etravirine

Axitinib's FDA label of March 12, 2026 names etravirine in its drug interactions section; the etravirine label PlainMeds reads does not name axitinib. The axitinib label: “Moderate CYP3A4/5 inducers may also reduce the plasma exposure of axitinib and should be avoided if possible.”

Check it at the source: the axitinib FDA label on DailyMed (effective March 12, 2026, U.S. Pharmaceuticals); the etravirine FDA label on DailyMed (effective August 15, 2023, Janssen Products LP).

What does the axitinib label say about etravirine?

Axitinib label, drug interactions

Moderate CYP3A4/5 inducers (e.g., bosentan, efavirenz, etravirine, modafinil, and nafcillin) may also reduce the plasma exposure of axitinib and should be avoided if possible.

Source: FDA drug label (INLYTA), NDA202324 (Pf Prism Cv), as published by U.S. Pharmaceuticals, effective March 12, 2026 (SPL set 8a903e31-936e-4ed7-8a59-59f32374f338), via openFDA; the full label on DailyMed

What does the etravirine label say about axitinib?

Etravirine's label (effective August 15, 2023) does not name axitinib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Intelence), Janssen Products LP, effective August 15, 2023 (SPL set 6a9cbc29-9f15-4b24-8d86-206b82887f3d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Axitinib generic labelers
5Etravirine generic labelers
AxitinibEtravirine
Labeled forn/aHIV
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$9.94 per tablet 200 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?